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AGI-5198
CAS No. 1355326-35-0
AGI-5198 ( (IDH-C35) )
产品货号. M11453 CAS No. 1355326-35-0
AGI-5198 is the first highly potent and selective inhibitor of IDH1 R132H/R132C mutants with IC50 of 0.07 μM/0.16 μM.
纯度: >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥259 | 有现货 |
|
| 10MG | ￥421 | 有现货 |
|
| 50MG | ￥624 | 有现货 |
|
| 100MG | ￥1021 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称AGI-5198
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述AGI-5198 is the first highly potent and selective inhibitor of IDH1 R132H/R132C mutants with IC50 of 0.07 μM/0.16 μM.
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产品描述AGI-5198 is the first highly potent and selective inhibitor of IDH1 R132H/R132C mutants with IC50 of 0.07 μM/0.16 μM.
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同义词(IDH-C35)
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通路Metabolic Enzyme/Protease
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靶点Dehydrogenase
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受体R132C-IDH1; R132H-IDH1
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研究领域Cancer
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适应症——
化学信息
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CAS Number1355326-35-0
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分子量462.57
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分子式C27H31FN4O2
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纯度>98%(HPLC)
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溶解度Ethanol: 14 mg/mL (30.26 mM); DMSO: 24 mg/mL (51.88 mM)
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SMILESO=C(NC1CCCCC1)C(N(C2=CC=CC(F)=C2)C(CN3C=CN=C3C)=O)C4=CC=CC=C4C
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化学全称N-cyclohexyl-2-(N-(3-fluorophenyl)-2-(2-methyl-1H-imidazol-1-yl)acetamido)-2-(o-tolyl)acetamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Rohle D, et al. Science, 2013, 340(6132), 626-630.
产品手册
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